Which symptom would most likely indicate polyuria?

The symptom that most strongly indicates polyuria is characterized by a higher frequency of urination accompanied by an increased volume of urine produced. Polyuria is defined as excessive urination, typically more than 3 liters in a day. This condition can arise due to various factors, including diabetes mellitus, diabetes insipidus, or certain medications.

When considering the correct response, the combination of both high frequency and high volume of urination distinctly aligns with the definition of polyuria. Frequent urination, coupled with significant urine output, is a hallmark sign of this condition, as the body is unable to concentrate urine properly, resulting in both an increase in the number of trips to the bathroom and a larger amount of urine being produced at each visit.

The other symptoms provided do not meet the criteria for polyuria. Frequent urination with low volume suggests a different issue, perhaps related to bladder irritation or infection, while infrequent urination with high volume indicates an entirely different urinary issue and does not align with the characteristics of polyuria. Painful urination is typically associated with conditions like urinary tract infections and does not reflect the increased urine output seen in polyuria. Thus, the correct answer captures both essential aspects of polyuria—volume and frequency.