Which of the following is not a complication of cold applications?

In the context of cold applications, the correct response indicates that infection is not typically associated with the use of cold therapy. Cold applications, such as ice packs or cold compresses, are primarily used to reduce swelling, inflammation, and pain following injury or surgery. They help by causing vasoconstriction, which can limit the movement of fluids into the affected area and decrease metabolic activity and tissue demand for oxygen.

Unlike heat applications, cold therapies are generally considered safe and non-invasive when used appropriately. Complications like pain, burns, and blisters can arise if the cold application is applied for too long, improperly wrapped, or placed directly against the skin without protection. These situations can lead to tissue damage and discomfort. On the other hand, the risk of infection is not typically a direct consequence of cold therapy. Instead, infections are more commonly related to open wounds or injuries rather than the cold applications themselves. Thus, infection is the least likely complication associated with cold applications, making this the correct choice.